You are rated a score at the end of your run. Your score helps you progress the game, and is used to determine your place on the daily challenge leaderboards.
The table below is additive scoring (for each action performed).
| Name | Description | Score |
|---|---|---|
| Floors Climbed | Number of the Floor you reached (including the narrative Floor 51) | 5 per floor |
| Enemies Killed | For each normal encounter defeated | 2 per enemy |
| Exordium Elites Killed | For each killed Elite in the Exordium | 10 per Elite |
| City Elites Killed | For each killed Elite in the City | 20 per Elite |
| Beyond Elites Killed | For each killed Elite in the Beyond | 30 per Elite |
| Bosses Slain | For each defeated Boss | 50+* per Boss |
| Ascension | 5% score per Ascension level | 5%** per level |
| Champion | Defeat an Elite without taking damage. | 25 per Elite |
| Perfect | Defeat a Boss without taking damage. | 50 per Boss |
| Beyond Perfect | Defeat 3 bosses without taking damage (overrides Perfect). | 200 |
| Heartbreaker | Defeat the Heart. | 250 |
| Collector | Have 4 copies of any non-starter card. | 25 per set |
| Librarian | Deck size greater than 35 cards. | 25 |
| Encyclopedian | Deck size greater than 50 cards (overrides Librarian). | 50 |
| Overkill | Deal 99 damage with a single attack. | 25 |
| Mystery machine | Traveled to 15+ ? rooms. | 25 |
| I Like Shiny | Have 25 or more relics. | 50 |
| Well Fed | Increased your Max HP by 15 or more. | 25 |
| Stuffed | Increased your Max HP by 30 or more (overrides Well Fed). | 50 |
| Money Money | Accrued 1,000 or more gold. | 25 |
| Raining Money | Accrued 2,000 or more gold. | 50 |
| I Like Gold | Accrued 3,000 or more gold. | 75 |
| C-c-c-combo | Play 20 cards in a single turn. | 25 |
| Pauper | Have 0 rare cards. | 50 |
| Speedster | Victory in under 60 minutes. | 25 |
| Light Speed | Victory in under 45 minutes (overrides Speedster). | 50 |
| Curses! | Your deck contains 5 curses. | 100 |
| Highlander | Your deck contains no duplicates (excluding starter cards). | 100 |
| On My Own Terms | Killed yourself. | 50 |
| Poopy | Received the Spirit Poop. | (-1) |
* The bonus increases by 50 for each boss defeated, so the first is worth 50 points, the second 100 points, and so on.
** The Ascension score multiplier only applies to the score from the following bonuses: Floors Climbed, Enemies Killed, Elites Killed, Bosses Slain, Champion, Perfect, Beyond Perfect, Overkill, and C-c-c-combo.
Patch 9 added Ascension mode. Ascension Mode adds a 5% score bonus per Ascended level. Note that Ascension mode has to be unlocked by beating the game with a character.