Relics are permanent items that provide a passive bonus for the rest of the run. Most relics are available to all characters, with some exceptions (indicated in the Rarity column).
Starter Relics are granted upon starting a run with the corresponding character.
Common, Uncommon, and Rare Relics can be found from a variety of sources.
Boss Relics can only be found from Bosses (or in Neow's starting choice, traded for Starter Relic).
Event Relics can only be found from specific event outcomes.
Collection
Starter: Characters can start with these relics.
Burning Blood (Ironclad only): At the end of combat, heal 6 HP.Cracked Core (Defect only): At the start of each Combat, Channel 1 Lightning.Ring of the Snake (Silent only): At the start of each combat, draw 2 additional cards.
Common: Weak relics that are found commonly.
Ancient Tea Set: Whenever you enter a Rest Site, start the next combat with 2 Energy. Art of War: If you do not play any Attacks during your turn, gain an extra Energy next turn. Bag of Marbles: At the start of each combat, apply 1 Vulnerable to ALL enemies. Bag of Preparation: At the start of each combat, draw 2 additional cards. Data Disk (Defect only): Start each combat with 1 Focus. Happy Flower: Every 3 turns, gain 1 Energy. Maw Bank: Whenever you climb a floor, gain 12 Gold. No longer works when you spend any Gold at the shop. Oddly Smooth Stone: At the start of each combat, gain 1 Dexterity. Potion Belt: Upon pickup, gain 1 Potion slot. Regal Pillow: Heal an additional 15 HP when you Rest. Relic: Whenever you would deal 4 or less unblocked Attack damage, increase it to 5.
Uncommon: Stronger relics which appear less often than common relics.
Darkstone Periapt: Whenever you obtain a Curse, increase your Max HP by 6. Frozen Egg: Whenever you add a Power card to your deck, it is Upgraded. Gold-Plated Cables (Defect only): Your rightmost Orb triggers its passive an additional time. Meat on the Bone: If your HP is at or below 50% at the end of combat, heal 12 HP. Mercury Hourglass: At the start of your turn, deal 3 damage to ALL enemies. Molten Egg: Whenever you add an Attack card to your deck, it is Upgraded. Self-Forming Clay (Ironclad only): Whenever you lose HP in combat, gain 3 Block next turn. Smiling Mask: The merchant's card removal service now always costs 50 Gold. Symbiotic Virus (Defect only): At the Start of each combat, Channel 1 Dark. The Courier: The merchant no longer runs out of cards, relics, or potions and his prices are reduced by 20%. Toxic Egg: Whenever you add a Skill card to your deck, it is Upgraded.
Rare: Unique and powerful relics which are rarely seen.
Bird-Faced Urn: Whenever you play a Power, heal 2 HP. Charon's Ashes (Ironclad only): Whenever you Exhaust a card, deal 3 damage to ALL enemies. Du-Vu Doll: For each Curse in your deck, start each combat with 1 additional Strength. Emotion Chip (Defect only): At the start of each turn, if you took any damage last turn, trigger the passive ability of all your Orbs. Girya: You can now gain Strength at Rest Sites. (3 times max) Incense Burner: Every 5 turns, gain 1 Intangible. Stone Calendar: At the end of turn 7, deal 40 damage to ALL enemies. The Specimen (Silent only): Whenever an enemy dies, transfer any Poison it has to a random enemy. Thread and Needle: At the start of each combat, gain 5 Plated Armor. Unceasing Top: Whenever you have no cards in hand during your turn, draw a card.
Boss: Relics found only within Boss chests.
Black Star: Elites now drop 2 Relics when defeated. Busted Crown: Gain 1 Energy at the start of each turn. On Card Reward screens, you have 2 fewer cards to choose from. Calling Bell: Obtain 3 Curses and 3 Relics. Coffee Dripper: Gain 1 Energy at the start of each turn. You can no longer Rest at Rest Sites. Empty Cage: Upon pickup, remove 2 cards from your deck. Frozen Core (Defect only): Replaces Cracked Core. If you end your turn with empty Orb slots, Channel 1 Frost. Hovering Kite (Silent only): Gain 1 Energy and discard 2 cards at the start of each turn. Mark of Pain (Ironclad only): Gain 1 Energy at the start of each turn. Start combats with 2 Wounds in your draw pile. Nuclear Battery (Defect only): At the start of each combat, Channel 1 Plasma. Philosopher's Stone: Gain 1 Energy at the start of each turn. ALL enemies start with 2 Strength. Ring of the Serpent (Silent only): Replaces Ring of the Snake. At the start of your turn, draw 1 additional card. Velvet Choker: Gain 1 Energy at the start of each turn. You cannot play more than 6 cards per turn.White Beast Statue: Potions always drop after combat. Wrist Blade (Silent only): Attacks that cost 0 deal 3 additional damage.
Event: Relics which can only be obtained through events.
Bloody Idol: Whenever you gain Gold, heal 5 HP. Cultist Headpiece: You feel more talkative. Relic: Raise your Max HP by 1 after each combat. Golden Idol: Enemies drop 25% more Gold. Gremlin Visage: Start each combat with 1 Weak Relic: The next non-boss chest you open is empty. Nilry's Codex: At the end of each turn, you can choose 1 of 3 random cards to shuffle into your draw pile. Odd Mushroom: When Vulnerable, take 25% more damage rather than 50%.
Shop: Relics which can only be purchased from the Merchant.
Chemical X: The effects of your cost X cards are increased by 2. Clockwork Souvenir: At the start of each combat, gain 1 Artifact. Dolly's Mirror: Upon pickup, obtain an additional copy of a card in your deck. Hand Drill: Whenever you break an enemy's Block, apply 2 Vulnerable. Lee's Waffle: Raise your Max HP by 7 and heal all of your HP. Meal Ticket: Whenever you enter a shop room, heal 7 HP. Orange Pellets: Whenever you play a Power, Attack, and Skill in the same turn, remove all your Debuffs. Runic Capacitor (Defect only): Start each combat with 3 additional Orb slots. Sling of Courage: Start each Elite combat with 2 Strength. Strange Spoon: Cards which Exhaust when played will instead discard 50% of the time. The Abacus: Gain 6 Block whenever you shuffle your draw pile. Toy Ornithopter: Whenever you use a potion, heal 3 HP. Twisted Funnel (Silent only): At the start of each combat, apply 4 Poison to ALL enemies.