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Potions are one-time-use items that can only be used in combat with the exception of Fruit Juice, Entropic Brew, and Blood Potion, which can be used in most scenarios. The player can typically hold up to 3 of them, or 2 on ascension levels 11 and higher. PotionBelt Potion Belt increases the number of potions you can hold by 2, which mean you can hold up to 5 potions with it, or 4 on ascension levels 11 and higher.

Using a potion does not require Energy and does not count as playing a card.

When a potion is offered to you, the rarity chances are:

  • 65% for a Common potion.
  • 25% for an Uncommon potion.
  • 10% for a Rare potion.

Obtaining Potions[]

  • Potions are occasionally dropped as a reward after combat. The default chance of a potion dropping is 40% and resets at the start of each Act. If a potion drops, the chance decreases by 10%. If a potion doesn't drop, the chance increases by 10%.
  • Bought at Merchant's Shop
  • If you reached the boss of the first Act, Neow may offer you 3 potions.
  • Some Events offer potions.
    • Lab offers you 3 random potions.
    • The Woman in Blue allows you to buy 1 random potion for 20 gold, 2 for 30 gold, and 3 for 40 gold.
    • Knowing Skull grants you a random potion at the cost of 10% of your HP, with 6 at minimum.
  • Using the card Alchemize creates 1 random potion
  • Obtaining Cauldron Cauldron offers you 5 random potions.
  • Obtaining TinyHouse Tiny House offers you 1 random potion.
  • EntropicBrew Potion Static Entropic Brew fills all your empty potion slots, including its slot, with random potions.
  • Obtaining Sozu Sozu prohibits you from obtaining any more potions, including potions obtained from EntropicBrew Potion Static Entropic Brew. However, you are still able to use potions you already have on you.

Other Interactions[]

  • We Meet Again! offers you a choice to give Ranwid 1 random potion you have in exchange for a Relic.
  • ToyOrnithopter Toy Ornithopter heals 5 HP whenever you use a potion.
  • SacredBark Sacred Bark doubles the effectiveness of potions except:
    • Ambrosia Ambrosia
    • Blessing Of The Forge temporary Blessing of the Forge
    • EntropicBrew Potion Static Entropic Brew
    • Elixir Elixir
    • GamblersBrew Gambler's Brew
    • SmokeBomb Smoke Bomb
    • StancePotion Stance Potion

List of Potions[]

Icon Name Rarity Effect
Ambrosia
Ambrosia Rare (Watcher only) Enter Divinity Stance.
AncientPotion
Ancient Potion Uncommon Gain 1 (SacredBark 2) Icon Artifact Artifact.
AttackPotion
Attack Potion Common Add (SacredBark 2 copies of) 1 of 3 random Attack cards to your hand, it costs (SacredBark They cost) 0 Energy this turn.
Blessing Of The Forge temporary
Blessing of the Forge Common Upgrade all cards in your hand for the rest of combat.
BlockPotion
Block Potion Common Gain 12 (SacredBark 24) Icon Block Block.
BloodPotion
Blood Potion Common (Ironclad only) Heal for 20% (SacredBark 40%) of your Max HP.
BottledMiracle
Bottled Miracle Common (Watcher only) Add 2 (SacredBark 4) Miracles to your hand.
Colorless Potion
Colorless Potion Common Choose 1 of 3 random Colorless cards to add (SacredBark 2 copies of it) to your hand, it costs (SacredBark They cost) 0 Energy this turn.
CultistPotion
Cultist Potion Rare Gain 1 (SacredBark 2) Icon Ritual Ritual.
CunningPotion
Cunning Potion Uncommon (Silent only) Add 3 (SacredBark 6) Upgraded Shivs to your hand.
DexterityPotion
Dexterity Potion Common Gain 2 (SacredBark 4) Icon Dexterity Dexterity.
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Distilled Chaos Uncommon Play the top 3 (SacredBark 6) cards of your draw pile.
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Duplication Potion Uncommon This turn, your next card is (SacredBark next 2 cards are) played twice.
Elixir
Elixir Uncommon (Ironclad only) Exhaust any number of cards in your hand.
EnergyPotion
Energy Potion Common Gain 2 (SacredBark 4) Energy.
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Entropic Brew Rare Fill all your empty potion slots with random potions.
EssenceOfDarkness
Essence of Darkness Rare (Defect only) Channel 1 (SacredBark 2) Dark Dark Orbs for each orb slot.
EssenceOfSteel
Essence of Steel Uncommon Gain 4 (SacredBark 8) Icon PlatedArmor Plated Armor.
ExplosivePotion
Explosive Potion Common Deal 10 (SacredBark 20) Damage to all enemies.
FairyinaBottle
Fairy in a Bottle Rare When you would die, heal to 30% (SacredBark 60%) of your Max HP instead and discard this potion.
FearPotion
Fear Potion Common Apply 3 (SacredBark 6) Icon Vulnerable Vulnerable.
FirePotion
Fire Potion Common Deal 20 (SacredBark 40) Damage to target enemy.
SteroidPotion
Flex Potion Common Gain 5 (SacredBark 10) Icon Strength Strength. At the end of your turn, lose 5 (SacredBark 10) Icon Strength Strength.
FocusPotion
Focus Potion Common (Defect only) Gain 2 (SacredBark 4) Icon Focus Focus.
FruitJuice
Fruit Juice Rare Gain 5 (SacredBark 10) Max HP.
GamblersBrew
Gambler's Brew Uncommon Discard any number of cards, then draw that many.
GhostInAJar
Ghost In A Jar Rare (Silent only) Gain 1 (SacredBark 2) Icon Intangible Intangible.
HeartofIron
Heart of Iron Rare (Ironclad only) Gain 6 (SacredBark 12) Icon Metallicize Metallicize.
LiquidBronze
Liquid Bronze Uncommon Gain 3 (SacredBark 6) Icon Thorns Thorns.
LiquidMemories
Liquid Memories Uncommon Choose a card (SacredBark 2 cards) in your discard pile and return it (SacredBark them) to your hand. It costs (SacredBark They cost) 0 Energy this turn.
PoisonPotion
Poison Potion Common (Silent only) Apply 6 (SacredBark 12) Icon Poison Poison to target enemy.
PotionofCapacity
Potion of Capacity Uncommon (Defect only) Gain 2 (SacredBark 4) Orb slots.
PowerPotion
Power Potion Common Add (SacredBark 2 copies of) 1 of 3 random Power cards to your hand, it costs (SacredBark They cost) 0 Energy this turn.
RegenPotion
Regen Potion Uncommon Gain 5 (SacredBark 10) Icon Regen Regeneration.
SkillPotion
Skill Potion Common Add (SacredBark 2 copies of) 1 of 3 random Skill cards to your hand, it costs (SacredBark They cost) 0 Energy this turn.
SmokeBomb
Smoke Bomb Rare Escape from a non-boss combat. Receive no rewards.
SneckoOil
Snecko Oil Rare Draw 5 (SacredBark 10) cards. Randomize the costs of all cards in your hand for the rest of the combat.
SpeedPotion
Speed Potion Common Gain 5 (SacredBark 10) Icon Dexterity Dexterity. At the end of your turn, lose 5 (SacredBark 10) Icon Dexterity Dexterity.
StancePotion
Stance Potion Uncommon (Watcher only) Enter Calm or Wrath.
StrengthPotion
Strength Potion Common Gain 2 (SacredBark 4) Icon Strength Strength.
SwiftPotion
Swift Potion Common Draw 3 (SacredBark 6) cards.
WeakPotion
Weak Potion Common Apply 3 (SacredBark 6) Icon Weak Weak.

Update History[]

  • Patch V2.0: The Watcher
    • Ironclad only, Uncommon Potion: Elixir Elixir
    • Ironclad only, Rare Potion: HeartofIron Heart of Iron
    • Silent only, Uncommon Potion: CunningPotion Cunning Potion
    • Defect only, Uncommon Potion: PotionofCapacity Potion of Capacity
    • Defect only, Rare Potion: EssenceOfDarkness Essence of Darkness
    • Watcher only, Common Potion: BottledMiracle Bottled Miracle
    • Watcher only, Uncommon Potion: StancePotion Stance Potion
    • Watcher only, Rare Potion: Ambrosia Ambrosia
    • Common Potion: Blessing Of The Forge temporary Blessing of the Forge
    • Common Potion: Colorless Potion Colorless Potion
    • Uncommon Potion: DistilledChaos Potion Static Distilled Chaos
    • Uncommon Potion: Duplication Potion Static Duplication Potion
    • Uncommon Potion: LiquidMemories Liquid Memories
    • Rare Potion: CultistPotion Cultist Potion
    • Common potion droprate decreased from 70% -> 65%.
    • Rare potion droprate increased from 5% -> 10%.
    • SneckoOil Snecko Oil reworked.
    • BloodPotion Blood Potion healing buffed from 10% -> 20%.
    • BloodPotion Blood Potion rarity changed from Uncommon -> Common.
    • FairyinaBottle Fairy in a Bottle healing buffed from 10% -> 30% HP.
    • FocusPotion Focus Potion rarity changed from Uncommon -> Common.
    • GhostInAJar Ghost in a Jar rarity changed from Uncommon -> Rare.
    • PoisonPotion Poison Potion is now Silent only.
    • Cards/powers/potions that generate now just describe them with a + in their name.
    • Several potions now have updated potion bottle assets.
    • Some potions are rainbow colored now. It's groovy.
      • Affected potions are DistilledChaos Potion Static Distilled Chaos, Duplication Potion Static Duplication Potion, and EntropicBrew Potion Static Entropic Brew.
    • Uncommon potions now have small circle particle effects.
    • Rare potions now have gold sparkly visual effects.
    • Wording updated for several relics, cards, potions, and powers to improve clarity.
    • EntropicBrew Potion Static Entropic Brew can now be used outside of combat.
    • Fixed EntropicBrew Potion Static Entropic Brew filling potions slots with Sozu Sozu.
    • Fixed Mayhem, Havoc, DistilledChaos Potion Static Distilled Chaos, and Omniscience sometimes not playing cards if original target is dead.
  • Patch V1.1: The Dealer
    • While the potion popup is open, the potion's tip is now displayed.
    • BloodPotion Blood Potion buffed to heal 10% -> 25%.
    • Potion menu is way bigger now (easier to click on for mouse/touchscreen).
    • Top panel gold icon, health icon, potion slots, and modifiers now scale up when hovered.
    • Fixing some grammar and typos in Potion popup text.
    • Tips for potions now show up when hovered in Reward screens and Shops (not just in the Potion panel after acquisition).
    • Fixed issue where up/down on controller in potion drink/discard also navigated to monsters/cards during combat.
    • Knowing Skull event can no longer give you a potion if you have the Sozu Sozu relic.
  • Weekly Patch 54: Loop
    • Fixed issue where BloodPotion Blood Potion wouldn't heal the player if used immediately after combat.
    • Fixed issue where EntropicBrew Potion Static Entropic Brew did not give players potions if used post-combat.
    • Fixed issue where potion seeds weren't persistent on save/load.
    • Fixed issue where ToyOrnithopter Toy Ornithopter relic wouldn't trigger outside of combat.
  • Weekly Patch 52: Release Date Price Increase
    • Fixed issue that allowed player to throw SmokeBomb Smoke Bomb in some rooms to no effect.
  • Weekly Patch 51: Recursion
    • Muzzle blight was applying twice to LizardTail Lizard Tail and FairyinaBottle Fairy in a Bottle.
    • Throwing a SmokeBomb Smoke Bomb at the Final Act boss no longer crashes the game.
  • Weekly Patch 44: Chrysalis
    • All sources of random temporary card generation in combat (like DeadBranch Dead Branch) can no longer generate cards that provide healing.
      • Alchemize is now categorized as a healing card.
    • New tip added to indicate that healing cards cannot be generated randomly during combat.
  • Weekly Patch 42: Reboot
    • Adding card, potion, relic, and heart icons that can appear in tips now. Used on Run History screen.
  • Weekly Patch 41: Chill
    • Fixed SmokeBomb Smoke Bomb and Colosseum bug that caused the player to go invisible.
  • Weekly Patch 40: Forethought
    • Removed two outdated tips about potions.
  • Weekly Patch 39: We Meet Again!
    • Potion throw targeting is no longer cancelled via click (you can still drag away or right click to cancel).
  • Weekly Patch 38: Bane
    • We Meet Again! event no longer allows the player to drink or discard the potion.
    • You can now drink FruitJuice Fruit Juice in more locations. (FruitJuice FRUIT JUICE REVOLUTION)
  • Weekly Patch 37: Darkness
    • Neow's Potion option now opens a reward screen with three potions.
  • Weekly Patch 36: Power Through
    • Fixed bug where We Meet Again! potion removal didn't apply for the left most slot.
  • Weekly Patch 35: Aggregate
    • AttackPotion Attack Potion, SkillPotion Skill Potion, and PowerPotion Power Potion now allow you to choose 1 of 3 cards (buff).
    • Updated SmokeBomb Smoke Bomb's use text from Drink -> Throw.
    • Fixed issue where potion targeting failed if the left most enemy was dead (controller only)
    • SmokeBomb Smoke Bomb now disables the end turn button so that enemies cannot attack you as you flee.
    • SmokeBomb Smoke Bomb no longer trigger Come at Me achievement.
  • Weekly Patch 34: Malaise
    • SneckoOil Snecko Oil potion buffed. Draw 2 -> 3 cards.
    • Fixed Save and Quit SmokeBomb Smoke Bomb exploit.
    • Using a SmokeBomb Smoke Bomb no longer gives the Champion score bonus.
  • Weekly Patch 33: Terror
    • GamblersBrew Gambler's Brew will no longer crash if used with no cards in hand.
  • Weekly Patch 32: Face Trader
    • Fixed FairyinaBottle Fairy in a Bottle and LizardTail Lizard Tail not triggering with Muzzle blight.
  • Weekly Patch 29: TURBO
    • Fixed issue where FairyinaBottle Fairy in a Bottle wouldn't heal you if max HP was less than 10.
    • SmokeBomb Smoke Bomb now work when fighting monsters in ? rooms.
    • Viewing potions during Discard/Draw Pile view no longer scrolls oddly.
  • Weekly Patch 28: The Ritual
    • Ascension 11 modifier changed. Instead of weakening potions, the player starts with 1 less potion slot.
  • Weekly Patch 27: Hello World
    • This week adds the long anticipated third character into the game!
    • New Uncommon Potion: FocusPotion Focus Potion (Defect Only)
  • Weekly Patch 26: Controller Support Testing
    • EntropicBrew Potion Static Entropic Brew now works properly with PotionBelt Potion Belt as intended.
  • Weekly Patch 25: Building Blocks
    • RegenPotion Regen Potion gets an overhaul. It now acts like Icon Poison Poison, but Icon Regen heals.
    • FruitJuice Fruit Juice can now be used outside of combat.
    • FruitJuice Fruit Juice will no longer spawn from Alchemize.
    • EntropicBrew Potion Static Entropic Brew can no longer spawn Fruit Juice.
    • EntropicBrew Potion Static Entropic Brew now spawns potions similarly to Alchemize now (considers rarity).
    • EntropicBrew Potion Static Entropic Brew now always gives you potions equal to your potion slot count.
    • SmokeBomb Smoke Bomb can no longer be incorrectly used outside of combat. (Can still be discarded)
    • SneckoOil Snecko Oil wording fix for high ascension levels.
    • GamblersBrew Gambler's Brew gets an updated color/shape.
    • DexterityPotion Dexterity Potion shape updated to match StrengthPotion Strength Potion.
  • Weekly Patch 24: Potions?!
    • 16 new potions were added and there are now different rarities for potions! We still have a few more goodies coming for potions in a later patch.
    • New Daily Mod: Brewmaster
    • Potion prices are now based on rarity (Common: 50, Uncommon: 75, Rare: 100)
    • Potions can now be character specific.
    • Potions now have rarity: Common, Uncommon, and Rare.
    • New Common Potion: AttackPotion Attack Potion.
    • New Common Potion: FearPotion Fear Potion.
    • New Common Potion: PowerPotion Power Potion.
    • New Common Potion: SkillPotion Skill Potion.
    • New Common Potion: SpeedPotion Speed Potion.
    • New Common Potion: SteroidPotion Steroid Potion.
    • New Rare Potion: EntropicBrew Potion Static Entropic Brew.
    • New Rare Potion: FairyinaBottle Fairy in a Bottle.
    • New Rare Potion: FruitJuice Fruit Juice.
    • New Rare Potion: SmokeBomb Smoke Bomb.
    • New Rare Potion: SneckoOil Snecko Oil.
    • New Uncommon Potion: BloodPotion Blood Potion (Ironclad Only.)
    • New Uncommon Potion: EssenceOfSteel Essence of Steel.
    • New Uncommon Potion: GamblersBrew Gambler's Brew.
    • New Uncommon Potion: GhostInAJar Ghost in a Jar (Silent Only.)
    • New Uncommon Potion: LiquidBronze Liquid Bronze.
    • Lowered Potion positions by 2px from top.
    • Updated coloring and image for many potions.
    • You can now discard potions during combat.
    • All potions that were in the game before this patch are Common.
      • Except RegenPotion Regen Potion and AncientPotion Ancient Potion, which are now Uncommon.
  • Weekly Patch 16: Back to Work
    • Relics and Potions in the shop now correctly set their prices when restocked with TheCourier the Courier.
  • Weekly Patch 13: Thinking Ahead
    • Sozu Sozu now prevents you from acquiring new potions rather than preventing usage (similar to Ectoplasm Ectoplasm).
    • Fixed bug where Nemesis could take more than 1 damage from Icon Thorns Thorns, Potions, and relics like LetterOpener Letter Opener.
  • Weekly Patch 11: A Library of Features
    • If you attempt to get a deprecated potion, you now get a FirePotion Fire Potion.
  • Weekly Patch 10: Quality of Life
    • Adding new AncientPotion Ancient Potion.
    • Removed Elixir Potion from the game.
  • Weekly Patch 6: We're Back!
    • Elixir potion buff: Now also affects .
  • Weekly Patch 5: Happy Holidays!
    • New Potion, Elixir.
    • Potions now save using their ID rather than their NAME (wasn't loading in other languages).
    • You can no longer open the potions dropdown if you're holding a card.
  • Weekly Patch 4: Full speed ahead!
    • Added a period at the end of RegenPotion Regen Potion's description.
  • Weekly Patch 2: Slimes!
    • DexterityPotion Dexterity Potion description updated for clarity/consistency.
    • StrengthPotion Strength Potion description updated for clarity/consistency.
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