Potions are one-time-use items that can only be used in combat with the exception of Fruit Juice, Entropic Brew, and Blood Potion, which can be used in most scenarios. The player can typically hold up to 3 of them, or 2 on ascension levels 11 and higher. PotionBelt Potion Belt increases the number of potion you can hold by 2, which mean you can hold up to 5 potions with it, or 4 on ascension levels 11 and higher.

Using a potion does not require Energy.

When a potion is offered to you, the rarity chances are:

  • 65% for a Common potion.
  • 25% for an Uncommon potion.
  • 10% for a Rare potion.

Obtaining PotionEdit

  • Potions are occasionally dropped as a reward after combat. The default chance of a potion dropping is 40% and resets at the start of each Act. If a potion drops, the chance decreases by 10%. If a potion doesn't drop, the chance increases by 10%.
  • Bought at Merchant's Shop
  • If you reached the boss of the first Act, Neow may offer you 3 potions.
  • Some Events offers potions.
    • Lab offers you 3 random potions.
    • The Woman in Blue allows you to buy 1 random potion for 20 gold, 2 for 30 gold, and 3 for 40 gold.
    • Knowing Skull grants you a random potion at the cost of 10% of your HP, with 6 at minimum.
  • Using the card Alchemize
    creates 1 random potion
  • Obtaining Cauldron Cauldron offers you 5 random potions.
  • Obtaining TinyHouse Tiny House offers you 1 random potion.
  • EntropicBrew Potion Entropic Brew fills all your empty potion slots, including its slot, with random potions.
  • Obtaining Sozu Sozu prohibits you from obtaining any more potion. However, you are still able to use potions you already have on you.

Other InteractionsEdit

  • Some Events may ask you for a potion in exchange for a reward.
    • We Meet Again! offers you a choice to give Ranwid 1 random potion you have in exchange for a Relic.
  • ToyOrnithopter Toy Ornithopter heals 5 HP whenever you use a potion.
  • SacredBark Sacred Bark doubles the effectiveness of potions except:
    • Ambrosia Ambrosia
    • Blessing Of The Forge temporary Blessing of the Forge
    • EntropicBrew Potion Entropic Brew
    • Elixir Elixir
    • GamblersBrew Gambler's Brew
    • SmokeBomb Smoke Bomb
    • StancePotion Stance Potion

List of PotionsEdit

Icon Name Rarity Effect
Ambrosia Rare (Watcher only) Enter Divinity Stance.
Ancient Potion Uncommon Gain 1 Icon Artifact Artifact.
Attack Potion Common Add 1 of 3 random Attack cards to your hand, it costs 0 this turn.
Blessing Of The Forge temporary
Blessing of the Forge Common Upgrade all cards in your hand for the rest of combat.
Block Potion Common Gain 12 Icon Block Block.
Blood Potion Common (Ironclad only) Heal for 20% of your Max HP.
Bottled Miracle Common (Watcher only) Add 2 Miracle
s to your hand.
Colorless Potion
Colorless Potion Common Choose 1 of 3 random Colorless cards to add to your hand, it costs 0 this turn.
Cultist Potion Rare Gain 1 Icon Ritual Ritual.
Cunning Potion Uncommon (Silent only) Add 3 Upgraded Shivs
to your hand.
Dexterity Potion Common Gain 2 Icon Dexterity Dexterity.
Distilled Chaos Uncommon Play the top 3 cards of your draw pile.
Duplication Potion Uncommon This turn, your next card is played twice.
Elixir Uncommon (Ironclad only) Exhaust any number of cards in your hand.
Energy Potion Common Gain 2 Energy.
Entropic Brew Rare Fill all your empty potion slots with random potions.
Essence of Darkness Rare (Defect only) Channel 1 Dark for each orb slot.
Essence of Steel Uncommon Gain 4 Icon PlatedArmor Plated Armor.
Explosive Potion Common Deal 10 Damage to all enemies.
Fairy in a Bottle Rare When you would die, heal to 30% of your Max HP instead and discard this potion.
Fear Potion Common Apply 3 Icon Vulnerable Vulnerable.
Fire Potion Common Deal 20 Damage to target enemy.
Focus Potion Common (Defect only) Gain 2 Icon Focus Focus.
Fruit Juice Rare Gain 5 Max HP.
Gambler's Brew Uncommon Discard any number of cards, then draw that many.
Ghost In A Jar Rare (Silent only) Gain 1 Icon Intangible Intangible.
Heart of Iron Rare (Ironclad only) Gain 6 Icon Metallicize Metallicize.
Liquid Bronze Uncommon Gain 3 Icon Thorns Thorns.
Liquid Memories Uncommon Choose a card in your discard pile and return it to your hand. It costs 0 this turn.
Poison Potion Common (Silent only) Apply 6 Icon Poison Poison to target enemy.
Potion of Capacity Uncommon (Defect only) Gain 2 Orb slots.
Power Potion Common Add 1 of 3 random Power cards to your hand, it costs 0 this turn.
Regen Potion Uncommon Gain 5 Regeneration.
Skill Potion Common Add 1 of 3 random Skill cards to your hand, it costs 0 this turn.
Smoke Bomb Rare Escape from a non-boss combat. Receive no rewards.
Snecko Oil Rare Draw 5 cards. Randomize the costs of all cards in your hand.
Speed Potion Common Gain 5 Icon Dexterity Dexterity. At the end of your turn, lose 5 Icon Dexterity Dexterity.
Stance Potion Uncommon (Watcher only) Enter Calm or Wrath.
Flex Potion Common Gain 5 Icon Strength Strength. At the end of your turn, lose 5 Icon Strength Strength.
Strength Potion Common Gain 2 Icon Strength Strength.
Swift Potion Common Draw 3 cards.
Weak Potion Common Apply 3 Icon Weak Weak to target enemy.

Update HistoryEdit

  • Patch V2.0: The Watcher
    • Ironclad only, Uncommon Potion: Elixir
    • Ironclad only, Rare Potion: Heart of Iron
    • Silent only, Uncommon Potion: Cunning Potion
    • Defect only, Uncommon Potion: Potion of Capacity
    • Defect only, Rare Potion: Essence of Darkness
    • Watcher only, Common Potion: Bottled Miracle
    • Watcher only, Uncommon Potion: Stance Potion
    • Watcher only, Rare Potion: Ambrosia
    • Common Potion: Blessing of the Forge
    • Common Potion: Colorless Potion
    • Uncommon Potion: Distilled Chaos
    • Uncommon Potion: Duplication Potion
    • Uncommon Potion: Liquid Memories
    • Rare Potion: Cultist Potion
    • Common potion droprate decreased from 70% -> 65%.
    • Rare potion droprate increased from 5% -> 10%.
    • Snecko Oil reworked.
    • Blood Potion healing buffed from 10% -> 20%.
    • Blood Potion rarity changed from Uncommon -> Common.
    • Fairy in the Bottle healing buffed from 10% -> 30% HP.
    • Focus Potion rarity changed from Uncommon -> Common.
    • Ghost in a Jar rarity changed from Uncommon -> Rare.
    • Poison Potion is now Silent only.
    • Cards/powers/potions that generate Upgraded Cards now just describe them with a + in their name.
    • Several potions now have updated potion bottle assets.
    • Some potions are rainbow colored now. It's groovy.
    • Uncommon potions now have small circle particle effects.
    • Rare potions now have gold sparkly visual effects.
    • Wording updated for several relics, cards, potions, and powers to improve clarity.
    • Entropic Brew can now be used outside of combat.
    • Fixed Entropic Brew filling potions slots with Sozu.
    • Fixed Mayhem, Havoc, Distilled Chaos, and Omniscience sometimes not playing cards if original target is dead.
  • Patch V1.1: The Dealer
    • While the potion popup is open, the potion's tip is now displayed.
    • Blood Potion buffed to heal 10% -> 25%.
    • Potion menu is way bigger now (easier to click on for mouse/touchscreen).
    • Top panel gold icon, health icon, potion slots, and modifiers now scale up when hovered.
    • Fixing some grammar and typos in Potion popup text.
    • Tips for potions now show up when hovered in Reward screens and Shops (not just in the Potion panel after acquisition).
    • Fixed issue where up/down on controller in potion drink/discard also navigated to monsters/cards during combat.
    • Knowing Skull event can no longer give you a potion if you have the Sozu relic.
  • Weekly Patch 54: Loop
    • Fixed issue where Blood Potion wouldn't heal the player if used immediately after combat.
    • Fixed issue where Entropic Brew did not give players potions if used post-combat.
    • Fixed issue where potion seeds weren't persistent on save/load.
    • Fixed issue where Toy Ornithopter relic wouldn't trigger outside of combat.
  • Weekly Patch 52: Release Date Price Increase
    • Fixed issue that allowed player to throw Smoke Bomb in some rooms to no effect.
  • Weekly Patch 51: Recursion
    • Muzzle blight was applying twice to Lizard Tail and Fairy Potion.
    • Throwing a Smoke Bomb at the Final Act boss no longer crashes the game.
  • Weekly Patch 44: Chrysalis
    • All sources of random temporary card generation in combat (like Dead Branch) can no longer generate cards that provide healing.
    • New tip added to indicate that healing cards cannot be generated randomly during combat.
  • Weekly Patch 42: Reboot
    • Adding card, potion, relic, and heart icons that can appear in tips now. Used on Run History screen.
  • Weekly Patch 41: Chill
    • Fixed Smoke Bomb and Colosseum bug that caused the player to go invisible.
  • Weekly Patch 40: Forethought
    • Removed two outdated tips about potions.
  • Weekly Patch 39: We Meet Again!
    • Potion throw targeting is no longer cancelled via click (you can still drag away or right click to cancel).
  • Weekly Patch 38: Bane
    • We Meet Again event no longer allows the player to drink or discard the potion.
    • You can now drink Fruit Juice in more locations. (FRUIT JUICE REVOLUTION)
  • Weekly Patch 37: Darkness
    • Neow's Potion option now opens a reward screen with three potions.
  • Weekly Patch 36: Power Through
    • Fixed bug where We Meet Again potion removal didn't apply for the left most slot.
  • Weekly Patch 35: Aggregate
    • Attack, Skill, and Power potions now allow you to choose 1 of 3 cards (buff).
    • Updated Smoke Bomb's use text from Drink -> Throw.
    • Fixed issue where potion targeting failed if the left most enemy was dead (controller only)
    • Smoke Bomb now disables the end turn button so that enemies cannot attack you as you flee.
    • Smoke Bombs no longer trigger Come at Me achievement.
  • Weekly Patch 34: Malaise
    • Snecko Oil potion buffed. Draw 2 -> 3 cards.
    • Fixed Save and Quit Smoke Bomb exploit.
    • Using a Smoke Bomb no longer gives the Champion score bonus.
  • Weekly Patch 33: Terror
    • Gambler's Brew will no longer crash if used with no cards in hand.
  • Weekly Patch 32: Face Trader
    • Fixed Fairy Potion and Lizard Tail not triggering with Muzzle blight.
  • Weekly Patch 29: TURBO
    • Fixed issue where Fairy Potion wouldn't heal you if max HP was less than 10.
    • Smoke Bombs now work when fighting monsters in ? rooms.
    • Viewing potions during Discard/Draw Pile view no longer scrolls oddly.
  • Weekly Patch 28: The Ritual
    • Ascension 11 modifier changed. Instead of weakening potions, the player starts with 1 less potion slot.
  • Weekly Patch 27: Hello World
    • This week adds the long anticipated third character into the game!
    • New Uncommon Potion: Focus Potion (Defect Only)
  • Weekly Patch 26: Controller Support Testing
    • Entropic Potion now works properly with Potion Belt as intended.
  • Weekly Patch 25: Building Blocks
    • Regen potion gets an overhaul. It now acts like Poison, but heals.
    • Fruit Juice can now be used outside of combat.
    • Fruit Juice will no longer spawn from Alchemize.
    • Entropic Brew can no longer spawn Fruit Juice.
    • Entropic Brew now spawns potions similarly to Alchemize now (considers rarity).
    • Entropic Brew now always gives you potions equal to your potion slot count.
    • Smoke Potion can no longer be incorrectly used outside of combat. (Can still be discarded)
    • Snecko Oil wording fix for high ascension levels.
    • Gambler's Brew (Potion) gets an updated color/shape.
    • Dexterity Potion shape updated to match Strength Potion.
  • Weekly Patch 24: Potions?!
    • 16 new potions were added and there are now different rarities for potions! We still have a few more goodies coming for potions in a later patch.
    • New Daily Mod: Brewmaster
    • Potion prices are now based on rarity (Common: 50, Uncommon: 75, Rare: 100)
    • Potions can now be character specific.
    • Potions now have rarity: Common, Uncommon, and Rare.
    • New Common Potion: Attack Potion.
    • New Common Potion: Fear Potion.
    • New Common Potion: Power Potion.
    • New Common Potion: Skill Potion.
    • New Common Potion: Speed Potion.
    • New Common Potion: Steroid Potion.
    • New Rare Potion: Entropic Brew.
    • New Rare Potion: Fairy in a Bottle.
    • New Rare Potion: Fruit Juice.
    • New Rare Potion: Smoke Bomb.
    • New Rare Potion: Snecko Oil.
    • New Uncommon Potion: Blood Potion (Ironclad Only)
    • New Uncommon Potion: Essence of Steel.
    • New Uncommon Potion: Gamblers Brew.
    • New Uncommon Potion: Ghost in a Jar (Silent Only)
    • New Uncommon Potion: Liquid Bronze.
    • Lowered Potion positions by 2px from top.
    • Updated coloring and image for many potions.
    • You can now discard potions during combat.
    • All potions that were in the game before this patch are Common.
    • Except Regen and Ancient potion, which are now Uncommon.
  • Weekly Patch 16: Back to Work
    • Relics and Potions in the shop now correctly set their prices when restocked with the Courier.
  • Weekly Patch 13: Thinking Ahead
    • Sozu now prevents you from acquiring new potions rather than preventing usage (similar to Ectoplasm).
    • Fixed bug where Nemesis could take more than 1 damage from Thorns, Potions, and relics like Letter Opener.
  • Weekly Patch 11: A Library of Features
    • If you attempt to get a deprecated potion, you now get a Fire Potion.
  • Weekly Patch 10: Quality of Life
    • Adding new Ancient Potion.
    • Removed Elixir Potion from the game.
  • Weekly Patch 6: We're Back!
    • Elixir potion buff: Now also affects Curses.
  • Weekly Patch 5: Happy Holidays!
    • New Potion, Elixir.
    • Potions now save using their ID rather than their NAME (wasn't loading in other languages).
    • You can no longer open the potions dropdown if you're holding a card.
  • Weekly Patch 4: Full speed ahead!
    • Added a period at the end of Regen potion's description.
  • Weekly Patch 2: Slimes!
    • Dexterity potion description updated for clarity/consistency.
    • Strength potion description updated for clarity/consistency.
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