Slay the Spire Wiki

Pain is a Curse.

While in hand, lose 1 HP when other cards are played, bypassing any Block. A deadly curse, even worse than Regret, as minimizing its damage is not often practical. This curse becomes a mixed blessing when used with self-harm cards including Rupture, Blood for Blood, CentennialPuzzle.png Centennial Puzzle, RunicCube.png Runic Cube and SelfFormingClay.png Self-Forming Clay

Cursed run.png Curse Cards Cursed run.png