Slay the Spire Wiki
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Tips

  • When combined with Sadistic Nature, envenom will trigger the additional damage on every hit you make, which can be extremely effective with any sort of shiv or multi-hit strategy.
  • Snecko Skull will effectively double the Icon Poison Poison inflicted by this card (and produce even more damage than that in the long term); in concert with a large number of attacks, this is one of the most effective ways to use that relic.
  • Envenom is extremely effective at removing stacks of Icon Artifact Artifact, since each hit counts as a separate debuff and expends an instance of Icon Artifact Artifact to prevent it.

Update History

  • Patch V1.1: The Dealer
    • Envenom's Poison is now applied immediately after the damage occurs.
  • Weekly Patch 42: Reboot
    • Updating icon for Envenom power.
  • Weekly Patch 5: Happy Holidays!
    • Envenom card gets a wording update for clarity.
    • Updating description for Envenom power to mention unblocked dmg.
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