Debuff

A debuff is a negative ongoing effect given to the character or an enemy by certain Cards, Relics, or Potions.

Debuffs can be negated by the Artifact Buff. Orange Pellets will remove all debuff on the character if the player successfully played Attack, Skill, and Power in the same turn.

Debuffs may stack by duration, lasting X turns, or by intensity, applying their effect with X power. Some debuffs do not stack at all.

Shared Debuffs

Debuffs that can be found from multiple sources in the game, both in the player's arsenal and from enemies.

• Debuffs
• Sources

Icon	Name	Effects	Stacks?
	Confused	The costs of your cards are randomized on draw, from 0 to 3.	No
	Dexterity (Negative)	Decreases Block gained from cards by X.	Intensity
	Dexterity Down	At the end of your turn, lose X Dexterity.	Intensity
	Focus (Negative)	Decreases the effectiveness of your Orbs by X.	Intensity
	Frail	Block gained from cards is reduced by 25%.	Duration
	No Draw	You may not draw any more cards this turn.	No
	Poison	At the beginning of its turn, the target loses X HP and 1 stack of Poison.	Intensity and Duration
	Shackled	At the end of its turn, regains X Strength.	Intensity
	Slow	The enemy receives (X*10)% more damage from attacks this turn. Whenever you play a card, increases X by 1.	Intensity
	Strength (Negative)	Decreases attack damage by X.	Intensity
	Strength Down	At the end of your turn, lose X Strength.	Intensity
	Vulnerable	Target takes 50% more damage from attacks.	Duration
	Weak	Target deals 25% less attack damage.	Duration

Icon	Name	Target	Cards	Enemy	Other
	Confused	Player		Snecko	Snecko Eye
	Dexterity (Negative)	Player		Lagavulin, Bear	Wraith Form
	Dexterity Down	Player			Duality, Speed Potion
	Focus (Negative)	Player	Reprogram, Hyperbeam	Spire Shield	Bias
	Frail	Player	Shame	Spike Slime, Spheric Guardian, Shelled Parasite, Snake Plant, Mystic, The Champ, The Collector, Maw, Time Eater (Ascension 19+), Corrupt Heart
	No Draw	Player	Battle Trance, Bullet Time
	Poison	Enemy	Deadly Poison, Poisoned Stab, Bouncing Flask, Crippling Cloud, Noxious Fumes, Corpse Explosion, Envenom		Twisted Funnel, Poison Potion
	Shackled	Enemy	Piercing Wail, Dark Shackles	Transient's Shifting
	Slow	Enemy		Giant Head	Time Dilation Modifier
	Strength (Negative)	Enemy	Disarm, Piercing Wail, Malaise, Dark Shackles
		Player		Lagavulin, Spire Shield
	Strength Down	Player	Flex, Mutagenic Strength		Flex Potion
	Vulnerable	Enemy	Bash, Thunderclap, Uppercut, Shockwave, Terror, Beam Cell, Crush Joints (If used after a Skill card), Indignation (If used while in Wrath)		Bag of Marbles, Hand Drill (Whenever you break an enemy's Block). Fear Potion
		Player	Berserk	Red Slaver, Fungi Beast's Spore Cloud, Gremlin Nob, The Guardian, Chosen, Snecko, The Champ, The Collector, Writhing Mass, Time Eater, Corrupt Heart
	Weak	Enemy	Clothesline, Intimidate, Shockwave, Uppercut, Neutralize, Sucker Punch, Crippling Cloud, Leg Sweep, Malaise, Go for the Eyes (If target intends to attack), Sash Whip (If used after an Attack card), Wave of the Hand (Whenever you gain Block that turn after using it)		Red Mask, Champion Belt (Whenever you apply Vulnerable), Weak Potion
		Player	Doubt	Green Louse, Acid Slime, Fat Gremlin, Blue Slaver, The Guardian, Chosen, Snake Plant, The Champ, The Collector, Maw, Writhing Mass, Time Eater, Corrupt Heart	Gremlin Visage

Unique Debuffs

Debuffs that comes from a single source.

Icon	Name	Target	Sources	Effects	Stacks?
	Bias	Player	Biased Cognition	At the start of your turn, lose X Focus.	Intensity
	Block Return	Enemy	Talk to the Hand	Whenever you attack this enemy, gain X Block.	Intensity
	Choked	Enemy	Choke	Whenever you play a card this turn, the targeted enemy loses X HP.	Intensity
	Constricted	Player	Spire Growth	At the end of your turn, take X damage.	Intensity
	Corpse Explosion	Enemy	Corpse Explosion	On death, the enemy deals X times its Max HP worth of damage to all other enemies.	Intensity
	Draw Reduction	Player	Time Eater	Draw 1 less card next X turns.	Duration
	Entangled	Player	Red Slaver	You may not play any Attacks this turn.	No
	Fasting	Player	Fasting	Gain X less Energy at the start of each turn.	Intensity
	Hex	Player	Chosen	Whenever you play a non-Attack card, add X Dazed to your draw pile.	Intensity
	Lock-On	Enemy	Bullseye	Lightning and Dark orbs deal 50% more damage (rounded down) to the targeted enemy.	Duration
	Mark	Enemy	Pressure Points	Whenever you play Pressure Points, all enemies with Mark lose X HP.	Intensity
	No Block	Player	Panic Button	You may not gain Block from cards for the next X turns.	Duration
	Wraith Form	Player	Wraith Form	Lose X Dexterity at the start of your turn.	Intensity