Blights are negative relics that are forced on the player each time they defeat 3 boss fights in Endless Mode.

List of BlightsEdit

Image Title Description
Accursed Accursed Whenever you defeat a Boss, obtain 2 random Curses.
Ancient Ancient Augmentation Enemies start combat with 1 Icon Artifact Artifact, 10 Icon PlatedArmor Plated Armor and 10 Regenerate.
Durian Durian Lose 50% of your Max HP.
Hauntings Hauntings Enemies start combat with 1 Icon Intangible Intangible.
Trophy Grotesque Trophy Upon pickup, obtain 3 Prides
Mimic Mimic Infestation Treasure rooms in future acts are replaced by Elites. Elites no longer drop relics.
Muzzle Muzzle You can no longer increase your Max HP. All healing is halved.
Scatter Scatterbrain Draw 1 less card a turn.
Spear Spear of Blight Enemies deal 100% more damage.
Shield Shield of Blight Enemies have 50% more HP.
Time Maze Time Maze You cannot play more than 15 cards per turn.
Twist Twisting Mind At the end of your turn, add 1 random Status card to the top of your draw pile.
Void essence Void Essence Lose 1 Energy permanently.

Order they are obtainedEdit

Set 1:Edit

Spear of Blight starts at a 100% increase

Shield of Blight starts at a 50% increase

Mimic Infestation

Set 2:Edit

Spear of Blight increases from 100% to 175%

Shield of Blight increases from 50% to 100%

Time Maze

Set 3: Edit

Spear of Blight increases from 175% to 250%

Shield of Blight increases from 100% to 150%


Set 4+: Edit

Spear of Blight increases by 75% each set

Shield of Blight increases by 50% each set

Grotesque Trophy each set

Update HistoryEdit

  • Weekly Patch 54: Loop
    • Blight rolling now increments relic rng seeds correctly (consistency on save/load)
  • Weekly Patch 51: Recursion
    • Muzzle blight was applying twice to Lizard Tail and Fairy Potion.
  • Weekly Patch 40: Forethought
    • Shifting Power (Transient) should now interact correctly, even if the owner has Artifact.
  • Weekly Patch 36: Power Through
    • Improved blight stacking for Endless. Grotesque Trophy is just 1 blight now.
  • Weekly Patch 33: Terror
    • Endless mod added to Custom Mode. Enemies get stronger and stronger.
    • Blight Chests mod added to Custom Mode. Boss chests give unique unavoidable blights for added challenge.
  • Weekly Patch 32: Face Trader
    • Fixed Fairy Potion and Lizard Tail not triggering with Muzzle blight.
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